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MainThromboelastometry

Thromboelastometry

The method of assessment of system of a hemostasis based on continuous graphic recording of stability of clots in time of their formation and the subsequent fibrinolysis.

Tests of a tromboelastogramma give more exact and volume information, than the tests of a routine coagulogram reflecting only changes in a procoagulant link.

Advantages of a tromboelastometry:

Not only the heating-up period of a clot, but also its quality, quantity, stability are defined. The method displays kinetics of all stages of formation of a thrombus.

All components making a clot are estimated: formulated elements of a blood (thrombocytes, erythrocytes), fibrin.

Direct and exact identification of a hyper fibrinolysis.

Assessment of influence of anticoagulants (heparin) on a hemostasis.

Definition of quantitative and qualitative defects of polymerization of fibrin.

An opportunity to estimate degree of risk of tromboembolic episodes.

Allows to estimate quickly a condition of system of a hemostasis and to choose adequate therapy.

EX-TEM – activation of an external way of coagulation. The test is sensitive to:

To deficiency of factors of an external way;

To influence of thrombocytes on clot density;

To Thrombinum inhibitors;

To quantity and polymerization ability of a fibrinogen;

To deficiency of F XIII;

To hyperfibrinolysis.

IN-TEM – activation of an internal way of coagulation. The test is sensitive to:

To deficiency of factors of an internal way;

To anti-coagulative effects (heparin, Thrombinum inhibitors);

To influence of thrombocytes on clot density;

To amount of ipolimerisation ability of a fibrinogen;

To deficiency of F XIII;

To hyperfibrinolysis.

FIB-TEM – the isolated fibrinogen contribution to clot density. The test is sensitive to:

To amount of ipolimerizatsionny ability of a fibrinogen;

To deficiency of F XIII;

To hyperfibrinolysis.

Allows to define, the insufficient level of a clot is formed due to shortage (depression of polymerization ability) of a fibrinogen or because of a disadvantage of a platelet contribution to a hemostasis. 

It is compared to EX-TEM.

HEP-TEM – shows existence or lack of a free heparin in a blood.

Assessment of the general level of a hemostasis without influence of a heparin. In combination with IN-TEM – the qualitative analysis of presence of a heparin (or a low-molecular heparin).

Allows to define, the extended time of a clot formation is caused by existence of a free heparin or deficiency of factors of a blood coagulation.

It is compared to IN-TEM

AP-TEM - shows presense or  lack of a hyperfibrinolysis.

The exclusive test drawing the accurate conclusion about existence of a hyper fibrinolysis. And also shows as far as treatment of an antifibrinolysis factors will be effective.

It is compared to EX-TEM.  

Material: blue blood.

Method: kinetics

ROTEM delta, Germany test systems.

Term of implementation of the analysis: 1 hour

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